How does the cartoon indicate that native Americans, as well as Europeans, used tobacco

They smoked it

Explanation:

In the attached cartoon, one sees an advertisement for tobacco in England for Virginia tobacco. Going by the text in the advertisement as well as the picture of the men smoking, it is seen that both Native Americans as well as Europeans used tobacco in their smoking pipes for a smoke.

Indeed, Native Americans have been known to have been smoking tobacco for a long time before the Europeans came but with the Europeans making more potent versions, they switched to that of Europeans.

fairly positive it is 4