What was the major issue between the North and the South starting in the 1850s?
A. industry
B. cotton
C. slavery
D. women's rights

The answer is slavery.

Here is cited proof:

The article "The American Civil War" by ReadWorks illustrates, "The major issue between  the North and the South was slavery. Starting in the 1850s, Northerners became more and  more hostile to the idea of slavery on moral grounds, while slavery continued to be an  accepted fact of life in the South."(1).

federal appellate courts are called courts of appeals. cases can be further appealed to the u.s. supreme court. cases are heard for the first time in a trial court. if either party disagrees with the decision in the trial court, they can appeal, asking a higher court to review the decision.

im pretty sure it has something to do with the end of ww1