How did a change in the environment affect the lives of Paleo Indians? It led to desertification of the region and forced the migration of humans in the area O li created a warmer climate that exposed people of the time to a greater variety of plant and animal life as resources. Olt led to a fluctuating climate and instability in the lives of the people of the time period. oli cooled down down the region, allowing larger, slow moving animals to be available to people of the period. -​