How did the mexican-american war affect the missouri compromise?

when claiming statehood, the territories in the southwest gained through the war claimed lands on both sides of missouri's border which caused unbalance between free and slaveholding states.
the territories gained through the mexican-american war increased the population in missouri, and the population reduction reached during the earlier compromise was no longer needed or wanted.
almost half of the territories gained during the war were canadian territories, which resumed the arguments in congress about which territories should be admitted as new states and which should not.
because france fought with the united states during the war, their government felt the debt owed to them by america should increase and should be included as part of a new compromise between the countries.