What is the result of the shift in equilibrium of the hemoglobin tetramer from the T state to the R state

substitution is the answer in this case

b tumor cells have a cell wall instead of a membrane

explanation:

tumor cells different from normal cells because tumor cells have a cell wall instead of a membrane.

the oldest known insects are believed to live around 400 millions ago as suggested by the fossil records.   some plants having woody stems also evolved during this time.

after the evolution of insects the first four legged species or the tetrapods evolved in shallow freshwater habitats from the intermediate species approximately 397 million years ago. the tetrapods went on conquering the land giving rise to amphibians, reptiles, mammals and birds.

the major split in tetrapods first occurred 340 million years ago branching off from amphibians.

363 million years ago when the carboniferous period began the insects started roaming on land and taking flights, following which the four limbed tetrapods adapted in the terrestrial habitat.