The various parts of the endomembrane system serve different functions in the cell. in this activity, you will identify the roles of each part of the endomembrane system. match each function to the appropriate bin.1. protein synthesis2. protein modification and sorting 3. macromolecule digestion4. lipid synthesis 5. autophagy 6. cisternal maturation 7. calcium ion storage8. poison detoxification a. smooth erb. rough er c. golgi apparatus d. lysosomes

1. protein synthesis - (b) rough ER

2. protein modification and sorting - (c) Golgi apparatus

3. macromolecule digestion - (d) lysosomes

4. lipid synthesis - (a) smooth ER

5. autophagy - (d) lysosomes

6. cisternal maturation - (c) Golgi apparatus

7. calcium ion storage - (a) smooth ER

8. poison detoxification - (a) smooth ER

Explanation:

Rough ER or rough endoplasmic reticulum with the help of ribosomes is responsible for protein synthesis and their subsequent transport to various other parts of the cell that is why both these organelles are also known as protein factory.

Soon after proteins are synthesized with the help of rough ER, they are transported to another network of organelle known as golgi apparatus. In golgi apparatus, the nascent protein is further modified and sorted. Modification and sorting of proteins help in identifying their final destination i.e. whether the protein is meant for mitochondria or plasma membrane or some other organelle. Maturation of cisternae also takes place in golgi apparatus.

Smooth ER or smooth endoplasmic reticulum is responsible for lipid synthesis, storage of calcium ions and poison detoxification. Most of the steroid hormones, triglycerols etc. are synthesized in the smooth endoplasmic reticulum. Smooth ER also stores calcium ions so that whenever they are required they can be sequestered back into the cytosol. Poison detoxification occurs in the smooth ER of liver because the enzymes present in the liver are capable of converting such hydrophobic substances into hydrophilic substances so that they could be easily secreted out of the body.

Lysosome is the organelle which is responsible for macromolecule digestion and autophagy. Lysosomes have very low pH and a lot of hydrolyzing enzymes which can easily digest macromolecules. Autophagy is a self degradable process in which damaged cells are eaten or destroyed by lysosomes so that their macromolecules could be broken down into their monomers so that they can be reused by our body.