Which of the following sentences would need to use the subjunctive mood when translated into spanish? i know that she will come. it's true that she will come. it's certain she will come. it's doubtful she will come.

 "It's doubtful she will come." 

The subjunctive is used to indicate some feeling towards a subject or uncertainty. 

In the first sentence, the verb "know" is used. If someone "knows" something then it is right to them, and the subjunctive is not used. 

In the second/third sentences, the adjectives true and certain are used. (Both of which are apparently synonyms to each other.) Since that there is certainty in these two examples, the subjunctive isn't used once again.

Ese hombre estaba conciente cuando dijo eso en el programa de vida real.