Prudence, indeed, will dictate that Governments long established should not be changed for light and transient causes; and accordingly all experience hath shewn, that mankind are more disposed to suffer, while evils are sufferable, than to right themselves by abolishing the forms to which they are accustomed. What is Jefferson saying here about overthrowing the government?

People have the right to overthrow their government whenever they feel like it

Explanation:

Jefferson saying about overthrowing the government is that people has the right to overthrow a government when they are not satisfy from their performance. People should not over throw a government just for one reason, if the government works against the will and prosperity of people and its country so the people has the right to overthrow the government.

the 4th option is the answer