What did queen isabella have to overcome in her life

Queen Isabella was the one of the only queens in the entire European countries/region who had financed Christopher Columbus's entire trip.

Also, she was not in the favor of people who were against the Catholic religion. So, she got rid of most of them who were not following it. 

Urban growth invariably feeds increased commercialization and industrialization. it requires continually expanding land areas. when urbanization rates are high, and countries do not have the institutional and managerial capacities or economic wherewithal to manage such rapid growths, they exert intense pressure on the types and nature of the resulting settlements. they contribute to the development of overcrowded slums and shanty towns without adequate essential services and necessary infrastructure.-by asit k. biswas and cecilia tortajada