Which statements best describe science? Check all that apply. Science involves oWhich statements best describe science? Check all that apply. Science involves observation and experimentation. Science is characterized by resistance to new information. Science is supported by facts and processes. Science involves the use of beliefs and opinions to construct explanations. Science continually changes and is constantly updated. bservation and experimentation. Science is characterized by resistance to new information. Science is supported by facts and processes. Science involves the use of beliefs and opinions to construct explanations. Science continually changes and is constantly updated.