Although Mistee was raised by her mother and grandmother, who both had histories of depression, she had a normal childhood. After college, she lands a high-stress job. She then becomes depressed. Mistee's psychopathology is best explained by the approach.

Diathesis-Stress model

Explanation:

The Diathesis-Stress model or approach attempts at explaining mental disease or psychopathologies by using a combitination of Diathesis, and stress models.

The word Diathesis refers to the medical predispositioned to having a disease. It is well-known that having relatives with psychopathologies makes a person more likely to have a mental disease, as it is the case with Mistee.

The Stress side of the approach tries to explain the emergence of the disease also due to a life event that could have caused a great degree of stress, such as having a high-stress job, as in Mistee's case.