The Tenth Amendment addressed the concerns of Anti-Federalists about A. individual freedoms. B. the meaning of the commerce clause. C. popular representation in Congress. D. the powers of state governments. E. the Electoral College.

D. the powers of state governments.

Explanation:

Tenth Amendment of the Constitution of the United States of America was initially mentioned as a  part of the Bill of Rights, granting the privileges "reserved" to the States. The last one among the ten amendments, it was primarily to alleviate the conflict and to relieve the concerns of state rights activists, who feared that the recently enacted Constitution would empower the federal government to implement unopposed power over states and their people.