Which of the following significant changes to a protocol could be administratively approved (in principle) by vvc? a. a change from non-survival to survival surgeryb. a change in the principal investigatorc. a change in the specific objectives for the projectd. a change in the analgesic agent administered

“Why are we wasting energy trying to distinguish between a minor amendment and

a major amendment?” asked Joanie Green,

the new IACUC senior administrator at

Great Eastern University. It seemed to her

that if there was a request to add a procedure to a protocol it was to be considered

an amendment, nothing more or less. “Are

you saying that adding a small subcutaneous

implant is as important as adding a cardiac

valve replacement?” asked Bob Thorne, a

clinical veterinarian. Green responded that

it had nothing to do with the level of difficulty or risk to an animal, but whether

or not there was a need for IACUC review.

the historians cited in the article all agree with one another about the cause of the civil war. despite coming from different backgrounds and cultures, the historians agree that slavery was the root cause of the civil war. the fact that all these historiansgenerally agree with one another makes their shared viewpoints more reliable and valid, especially because the historians have different backgrounds and all work for the well-respected institutions of howard university, clemson university, and the university of colorado.