When a business controlled all other businesses, what is it called?

The 2nd largest river in europe (that runs through 12 countries) is the river. question 13 options: rhine danube seine thames

Afull irb committee meeting is convened and one agenda item is a new research proposal to evaluate how mothers interact with their learning-disabled child. the inclusion criteria require the children to be a minimum of five years of age. the protocol requires the mother of the child to look at the child without any expression and not to talk to the child for three minutes. the committee determined that the mother's required task may upset the child. the irb approved the study with appropriate language in the parental permission form regarding the possibility that children might become upset. after the start of the study, the principal investigator reports to the irb that, as expected, one of the children became upset. the incident was handled according to the protocol and the child is fine. what should the irb do with regard to this report?

“dear sir: it is with great reluctance, i trouble you on a subject, which does not fall within your province; but it is a subject that occasions me more distress, than i have felt, since the commencement of the war; and which loudly demands the most zealous exertions of every person of weight and authority, who is interested in the success of our affairs. i mean the present dreadful situation of the army for want of provisions, and the miserable prospects before us, with respect to futurity. it is more alarming than you will probably conceive, for, to form a just idea, it were necessary to be on the spot. for some days past, there has been little less, than a famine in camp. a part of the army has been a week, without any kind of flesh, and the rest for three or four days. naked and starving as they are, we cannot enough admire the incomparable patience and fidelity of the soldiery, that they have not been ere this excited by their sufferings, to a general mutiny or dispersion. strong symptoms, however, discontent have appeared in particular instances; and nothing but the most acitive efforts every where can long avert so shocking a catastrophe.” what’s the central idea?