Diclofenac Patches are considered one of the
major transdermal patches
used as a pain killer. If the
patch was of circular shape
with radius of 2cm and the
thickness of the patch was
100 micro meter. The
release of diclofenac from
this dosage form showed a
lag time of 8.5 min.
calculate the total amount
of Diclofenac (mg) released
from the patch after 6hours,
if the concentration inside
the patch was 12.5mg/ml,
knowing that the partition
coefficient of the drug at
25°C is 10.5.
Select one:
a 326 mg
b. 112 58 mg
C. 107.56​