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Medicine, 31.03.2021 22:30 jalenshayewilliams

O cianeto de potássio (KCN) é um regente muito tóxico ao organismo, podendo levar a morte se injetado na corrente sanguínea. A toxicidade do cianeto é devida principalmente à ligação ao ferro no estado férrico (Fe
(III) ou Fe3+) da enzima citocromo oxidase mitocondrial (citocromo a-a3) da cadeia transportadora de elétrons.
O citocromo a-a3 regula a transferência de elétrons para o oxigênio molecular, o último passo da fosforilação
oxidativa antes da formação de ATP. Sabendo disso responda:
a) Qual complexo está sendo afetado pelo KCN?
b) Ao se ligar aos ions de Fe3+, o que o KCN está bloqueando?
c) O que acontece energeticamente após o KCN se ligar ao complexo?

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O cianeto de potássio (KCN) é um regente muito tóxico ao organismo, podendo levar a morte se injetad...

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