The principle effect of adh is to:
a. increase blood pressure in the glomerulus.
b. cause the release of renin.
c. inhibit aldosterone release.
d. increase the permeability of the distal convoluted tubule and collecting duct.

The correct answer is option D.

Explanation:

Antidiuretic hormone or ADH is a hormone which helps the body to maintain the amount of water by reducing the loss of water through urine. This hormone is secreted by the hypothalamus which is stored in the pituitary gland.  

The hormone acts by binding to the receptor which stimulates the insertion of "water channels" in the tubule membranes of kidney especially in Distal convoluted tubule and collecting duct. These kidney aquaporins help the absorption of water from the urine reducing the loss of water.  

Thus, option D is the correct answer.

D) increase the permeability of the distal convoluted tubule and collecting duct.

Explanation:

The principle of ADH is to increased in the permeability of the distal convoluted tubule and collected duct as, the action of ADH on receptors enhances the water permeability the and insertion of aquaporin AQP-2 channel in the cell membrane. The main function of the ADH is to conserved water through kidney and get released in posterior pituitary gland.

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