Is the opposite of an integer is always negative?

Positive integers are all the whole numbers greater than zero: 1, 2, 3, 4, 5, ... . Negative integers are all the opposites of these whole numbers: -1, -2, -3, -4, -5, …. We do not consider zero to be a positive or negative number. For each positive integer, there is a negative integer, and these integers are called opposites. For example, -3 is the opposite of 3, -21 is the opposite of 21, and 8 is the opposite of -8. If an integer is greater than zero, we say that its sign is positive. If an integer is less than zero, we say that its sign is negative. 

homozygous. one is homozygous, while two is heterozygous.

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