Considers a problem in the estimation of linkages in genetics. McLachlan and Krishnan (1997) also discuss this problem and we present their model. For our purposes, it can be described as a multinomial model with the four categories C1, C2, C3 , and C4 . For a sample of size n, let X = (X1, X2, X3 , X4 )′ denote the observed frequencies of the four categories. Hence, n = +4 i=1 Xi. The probability model is

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Step-by-step explanation:

the answer is:

the answer is:

to solve the problem, we need to remember the quotient of power property, it's defined by the following relation:

if we have a quotienf of powers that have the same base, we need to keep the same base and subtract the exponent of the denominator power to the exponent of the numerator power.

so, we are given the expression:

then, calculating we have:

hence, the answer is:

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