Lab tests of a new drug indicate a 70% success rate in completely curing the targeted disease. the doctors at the lab created the random data in the table using a representative simulation. the letter e stands for "effective," and n stands for "not effective." the estimated probability that it will take at least five patients to find one patient on whom the medicine would not be effective is (blank).

the estimated probability that the medicine will be effective on exactly three out of four randomly selected patients is (blank).