Why did european merchants eventually seek a sea route to asia?

One of the main reasons why European merchants eventually sought a sea route to Asia was because many Asian goods--especially spices--were in high demand in Europe, and trade routes over-land were extremely treacherous. 

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Cherokee  removal, part of the trail of tears, refers to the  forced  relocation between 1836 and 1839 of thecherokee  nation from  their lands ingeorgia, south carolina, north carolina, tennessee, texas, and alabama to the indian territory (present day oklahoma)  in  the thenwestern united states, and the resultant deaths