How did the fire-eaters differ from the Unionists? They supported Henry Foote for governor.
They wanted to secede over the issue of slavery.
They wanted to uphold the Compromise of 1850.
They opposed the Supreme Court’s Dred Scott decision.

They wanted to secede over the issue of slavery.

Explanation:

Unlike the Unionists who believe that the United States of America should remain together as one larger entity, the fire-eaters, however, believe in the secession of the United States. Fire eaters also favor slavery

Hence, in this case, the correct answer is, the fire-eaters differ from the Unionists in the sense that "They wanted to secede over the issue of slavery."

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