When did india become a direct colony of britain

England and the United Netherlands formed joint-stock companies: the English ( later British ) East India Company ( in 1600 ) and the Dutch East India Company ( in 1602 ). Those companies carried out the lucrative spice trade. India was the most important market for the trade. The East India Company lost its power of government in 1858 when British India came under the rule of the Crown. After that, Queen Victoria took a title of Empress of India.
India became officially a British colony in 1858.

Hi! after fertilization occurs, the zygote goes through mitosis and then differentiation (aka specialization of cells) to have a variety of cells that perform different functions. this allows for the creation of tissues and so on, all of which were once stem cells with no specific function.i hope i !