What happened when missouri applied for statehood?

a. it immediately became a state.

b. a major political crisis ensued.

c. few politicians acknowledge it.

d. it was turned down for lack of population.

The annexation of Missouri in to the US brought about the question of slavery in the Union. Granting Missouri statehood would unbalance the number of free and slave states in the Union, so I believe it's B. A major political crisis ensued, slavery being the "major political crisis."