What does this map show about the spread of the bubonic plague? see pic below.

it had no discernible pattern.

it followed common sea routes.

it traveled chiefly by land.

landlocked areas were the safest.

"It had no discernible pattern." is wrong, because there is a pattern, noticeably.

"It traveled chiefly by land" is also wrong, since we can see that the disease traveled by sea in the map.

"Landlocked Areas were the safest" is also wrong since there's a  hardly affected coastal area.

So in the end, we must go with It followed common sea routes.

Not only it is the correct one by elimination, considering that it cannot be any of the others, the pattern of the sea routes is very noticeable in the map, you just have to follow the red arrows to see it.

- tobacco.

- "rolfe reacted to consumer demand by importing seed from the west indies and cultivating the plant in the jamestown colony. those tobacco seeds became the seeds of a huge economic empire.the tobacco economy rapidly began to shape the society and development of the colony. growing tobacco takes its toil on the soil."

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i think they would live in caves or natural tunnels