In what ways did the relationship between whites and indians (powhatans) in virginia establish the pattern for later white-indian relations across north america?

The relationship or encounter between the whites and the Indians in Virginia went well at first. This established many of the patterns that characterized later Indian-white relations in North America, including disease, warfare, and removal. Indian societies undertook their own major changes due to disease, trade, and warfare. For a time after the Atlantic coastal tribes were nearly wiped out, the larger Indian peoples of the Appalachian area created a forbidding barrier to white expansion.