Who is more responsible for the Raping of Nanking, Japan's totalitarian regime for committing these atrocities or the rest of the world for not stopping Japan
before it got to this point?

it was the "4. potsdam" conference that demanded the unconditional surrender of japan, since it was clear that the japanese would continue to find until the very last man otherwise.

the option which was not a function of missionaries in the northwest was the first one - they established posts for trading furs and other goods.

missionaries were sent around the world to spread religion and their knowledge and others - they were not merchants who sold furs and other goods.