Which factor put the first settlers of Jamestown, VA at risk the most? A
Using slave labor to grow the economy

B
Trading tobacco as a form of currency

C
Being preoccupied with finding gold

D
Establishing trade with Native Americans

D Establishing trade with Native Americans

Explanation:

The English early settlers in Jamestown, Virginia, back in 1607 had series of struggles to contend with and overcome before they could settle fully in their new home. Some of the things that put them at risk the most were:

1. Insufficient food,

2. presence of disease and illness,

3. Establishing relations with the native Powhatan Indians

4. Inability to farm and perform other labor functions.

Hence, in this case, the correct answer is "Establishing trade with Native Americans."

first representative government in british america called virginia assembly