Which factors led to the end of the Mississippian culture? Check all that apply. Millions of American Indians died from new diseases. Chiefdoms broke apart as groups separated. Some people left their villages after chiefs became more powerful. Some groups moved their villages in order to trade. Most enslaved American Indians were sent to Europe.

1. Millions of American Indians died from new diseases.

2. Some groups moved their villages in order to trade

3. Chiefdoms broke apart as groups separated.

Explanation:

The Mississippian culture was known to have flourished before the European settlers came into the region. This was evident in the report of Hernando De Soto around the 1540s that describes the powerful chiefs ruling over large territories.

However, the Mississippian culture came to an end due to the following reasons:

1. Millions of American Indians died from new diseases which were brought by the European settlers such as smallpox, measles, and flu

2. Some groups moved their villages to trade: this occurred through the natives looking for what to trade in exchange for European goods such as guns and horses.

3. Chiefdoms broke apart as groups separated: consequently, the people separated looking for their immediate group instead of coming together at large.

i believe the answer would be 1.