How did European trade routes in the Eastern Hemisphere change after the 16th century?

they had to stopped being central and start finding new route places around such as Africa.

Explanation:

I did a little bit of research

julius caesar turned the roman republic into the roman empire by coming in and taking the "dictator" role during the time of a civil war (elites vs lower classes) winning battles and reputation, then declaring him dictator for life

hope this : )