When and why did the Roman Republic fall? What were some key differences between the Roman Republic and the Age of Augustus? What are some of the primary sources about the early Christians? What was revolutionary about early Christianity, from the Roman perspective?

What were some of the problems with which areas in the periphery of the Roman Empire had to deal in the second century CE?

Why do you have to ask such hard questions.

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.