In 1818, Andrew Jackson and Isaac Shelby negotiate the sale of land from which group of people?
A) British
B) Cherokees
C) Chickasaws
D) Spanish

Chickasaws

Explanation:

On October 19, 1818, state senator Jackson and former Governor of Kentucky Shelby, made the Treaty of Tuscaloosa (resulting in the Jackson Purchase) with the Chickasaw Indians.[1] Prior to the signing of the treaty, Levi Colbert (who, along with his brother George had taken over the leadership of the Chickasaw tribe), agreed to the land transfer, purportedly due to the acceptance of a bribe.[1] An uninhabited woodland area the tribe controlled (10,700 square miles of territory between the Mississippi River and the western valley of the Tennessee River) was traded for $300,000, to be paid in twenty annual installments.

i would say it is a and b.

hope this