What was the russian empires trade partners in 1450-1750

Major Maritime and Gunpowder Empires - Major maritime powers include Portugal, Spain, France, and England, and major Gunpowder Empires were the Ottoman, Ming and Qing China, the Mughal, Russia, Tokugawa, Songhay (Songhai), and Benin.

If i remember correctly it was caused by people hurling bodies at a country for some reason and them they all became infected