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explain the aspect of exploration and colonization that had the greatest impact on the native peoples of north and south america?

In both North America and South America, the european conquest was a disaster for the indigenous people because of the dissemination of diseases of european origin, such as influenza, smallpox and measles, for which they didn't have defenses.

These diseases wiped out about 95% of the native american population. In fact, some reaserchers have argued that the loss of native american life was so big that it actually resulted in a brief period of global cooling.

when world war i broke out across europe in 1914, president woodrow wilson proclaimed the united states would remain neutral, and many americans supported this policy of nonintervention. however, public opinion about neutrality started to change after the sinking of the british ocean liner lusitania by a german u-boat in 1915; almost 2,000 people perished, including 128 americans. along with news of the zimmerman telegram threatening an alliance between germany and mexico, wilson asked congress for a declaration of war against germany. the u.s. officially entered the conflict on april 6, 1917.