Which option most accurately explains the significance of the monroe doctrine?

Explanation:

Monroe Doctrine was a U.S. policy, opposing European colonialism in America. As textually says: "the manifestation of an unfriendly disposition toward the United States.". Also, this Doctrine also will respect and recognise all colonies that are already settle in the America.

So, basically Monroe Doctrine was to ensure a foreign policy against Europe.

demand is the need and oportunity to buy a given good or service.

four sitting presidents have been assassinated while in office but the first was abraham lincoln,