How did the fact that the safavids were shiite muslims affect relations with the ottomans?

The Safavid Empire´s religion was Shi'a Islam and all other religions, and forms of Islam were prohibited.  

For over a century the Ottoman Empire and Safavid Persia fought over the control of the South Caucasus and Mesopotamia and dogmatic disputes: the Ottomans were Sunnis and believed the Shia Muslims of the Qizilbash sect were heretics.

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the punishment for breaking the law would depend on the conditions or the seriousness of the law being broken, if he or she breaks the law while doing some great discovery or invention then it would classify as a scientific fraud. there are other words to describe the crime but scientific fraud would be the harshest one.