Who use the technique of mixing colors in oil and applying the paint to a wood panel to create the painting shown here? a. jan van eyck b. hans holbein, the elder c. cosimo de’ medici d. leonardo da vinci

D: Leonardo da Vinci hope it helps

the answer is a) james madison.

disease was the number one killer of native peoples. they had had little exposure to the diseases of europe. this led to some villages being almost completely wiped out and some tribes destroyed.