Which term containing a prefix, root, and suffix refers to a condition involving the chronic, progressive, and irreversible loss of the mind's cognitive and intellectual functions?

Dementia.

Explanation:

Dementia may be defined as the medical condition in which the thinking ability of the individual decreases with time. Dementia represents the large category of the different brain disease.

The individual suffers from the emotional issue, decrease in the motivation process and loss of coordination. The dementia involves the chronic represent the prefix, root means progressive and suffix means irreversible represents the different condition of the intellectual ability of brain in dementia.

Thus, the correct answer is dementia.