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Health, 19.09.2019 20:00 briandgonzalezk

Achild who suffers from a persistent viral infection is found to have a deficiency in lymphocyte production and very few t and b cells. other bone marrow-derived cells are produced in normal numbers, and mhc molecule expression on cells appears normal. transfusion of mature t cells from an unrelated donor who had recovered from a previous infection by the same virus would not be expected to the child clear his infection. which one of the following is a reasonable explanation for why this therapeutic approach would fail?
a. viral infections are cleared by antibodies, not t cells.
b. the patient's own immune system would destroy the transfused t cells before they could respond to the viral infection.
c. t cells recognize peptides, not viral particles.
d. donor t cell viral antigen recognition is restricted by mhc molecules not expressed in the patient.
e. in responding to the previous infection, the donor would have used up all his t cells specific for that virus.

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