The hearth of the Sino-Japanese cultural realm was probably... The Irrawaddy River. o The Indus River. o The Amazon River. The Mississippi River O The Yellow River

Correct answer is The Yellow River.

Explanation:

The Irrawaddy River is not correct as this river flows through Burma.

The Amazon River is not correct as this river flows through South America.

The Mississippi River is not correct as this river flows through United States.

The Yellow River is correct answer is correct answer as it refers to Huang He, one of the largest rivers in China. This is correct because Sino-Japanese culture is covering the area of China and Japan.

separation of church and state? not sure what you mean.