Why is the shape of the sickled cells an issue answer

The reason they have a sickled shape is that the underlying gene has the wrong instructions. These misshapen blood cells get clogged in vessels and don't have the life expectancy of normal blood cells. A person with sickle cell disease will experience fatigue (feeling tired) and have episodes of extreme pain, called a pain crisis. Sickled blood cells that block vessels in the brain can even cause a stroke.

I tried, hope this helps :)

the answer is: tabard inn, southwark.

in "the canterbury tales," by geoffrey chaucer, the twenty-nine diverse group of pilgrims is staying at a tavern in southwark, london, as they are traveling to canterbury. they wish to visit the relics of saint thomas becket in canterbury   cathedral in order to him for his when they underwent necessities.

invention of the washing machine

in the past, people used sticks and stones or scrub boards to clean their clothing. as it was sweaty, backbreaking work, we owe a world of to james king because he created the model for the modern washing machine in 1851. the most important issue was that this machine cleaned clothes while a person cranked the handle. doing this made people who used it develop strong muscles in their arms. later, in 1908, alva j. fisher created an electric washing machine named thor. this one was not the first automatic washing machine. however, it was one of the most popular models at the time.