Which of the following conditions will result in a reaction that is spontaneous at all temperatures?
a. positive enthalpy change and positive entropy change
b. negative enthalpy change and positive entropy change
c. positive enthalpy change and negative entropy change
d. negative enthalpy change and negative entropy change
d. liquid water is less dense than solid water

The answer is b. negative enthalpy change and positive entropy change. The reaction will always spontaneous to the heat decrease and entropy increase direction.

For cyclohexane compounds drawn in a chair conformation:   -axial bonds are vertical  -equatorial bonds are parallel to two bonds within the ring.  thus, as i assume the chair conformation is drawn:   -the x group is in an axial position, as are the five other vertical bonds.  -three axial bonds are on the top face of the ring  -the other three axial bonds are on the bottom face  the position of the second substituent on each ring carbon is equatorial.  gauche groups must be on an adjacent carbon such as carbon 6 and carbon 2, and also gauche groups are rotated by 60 degrees relative to each other.  drawing the newman projections for c1–c2 and c1–c6 aids in visualizing the groups that are gauche to the y group on c1.  click this link and watch some academic videos that may you more understand the topic