How do you explain in biochemistry: a lack of sleep causes a lack of energy

Insufficient sleep has been linked to an imbalanced increase in energy intake over expenditure, which leads to a positive energy balance and weight gain. Sleep quality may also moderate the relationship between physical activity and feelings of fatigue.

Chronic sleep loss can reduce the capacity of even young adults to perform basic metabolic functions such as processing and storing carbohydrates or regulating hormone secretion, report researchers from the University of Chicago Medical Center in the October 23 issue of The Lancet. Cutting back from the standard eight down to four hours of sleep each night produced striking changes in glucose tolerance and endocrine function -- changes that resembled the effects of advanced age or the early stages of diabetes -- after less than one week.

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