Put these steps in the mechanism of chymotrypsin catalysis in order from first to last. Note that your textbook may not break out each of these steps individually, but all steps should be ordered. (There will be eight steps.) A. His 57 catalyzes removal of H from Ser 195 hydroxyl.
B. His 57 donates H to N of sissile peptide bond, tetrahedral intermediate decomposes.
C. The portion (N-terminal end) of the original substrate with the new carboxylate terminus diffuses away.
D. Water donates H to His 57.
E. Resulting OH attacks carbonyl of remaining substrate.
F. His 57 donates H to Ser 195 O, leading to collapse of thtrahedral intermediate.
G. the portion (the C-terminal end) of original substrate with the new amino terminus diffuses away.
H. Ser 195's nucleophilic O attacks carbonyl C of substrate.

Nanotechnology, the field of trying to build ultrasmall structures one atom at a time, has progressed in recent years. one potential application of nanotechnology is the construction of artificial cells. the simplest cells would probably mimic red blood cells, the body's oxygen transporters. for example, nanocontainers, perhaps constructed of carbon, could be pumped full of oxygen and injected into a person's bloodstream. if the person needed additional oxygen-due to a heart attack perhaps, or for the purpose of space travel-these containers could slowly release oxygen into the blood, allowing tissues that would otherwise die to remain alive. suppose that the nanocontainers were cubic and had an edge length of 24 nanometers. part a part complete what is the volume of one nanocontainer? (ignore the thickness of the nanocontainer's wall.) express your answer using two significant figures. v v = 1.4ă—10â’20 l previous answers correct significant figures feedback: your answer 1.3824â‹…10â’20 = 1.382ă—10â’20 l was either rounded differently or used a different number of significant figures than required for this part. if you need this result for any later calculation in this item, keep all the digits and round as the final step before submitting your answer. part b suppose that each nanocontainer could contain pure oxygen pressurized to a density of 81 g/l . how many grams of oxygen could be contained by each nanocontainer?

When a scientific theory has been tested and proved by the scientific community, it becomes a law

Lab reagent, hypothesis test. a reference solution used as a lab reagent is purported to have a concentration of 5 mg/dl. six samples are taken from this solution and the following concentrations are recorded: (5.32, 4.88, 5.10, 4.73, 5.15, 4.75) mg/dl. these six measurements are assumed to be an srs of all possible measurements from solution. they are also assumed to have a standard deviation of 0.2, a normal distributin, and a mean concentration equal to the true concentration of the solution. carry out a significance test to determine whether these six measurements provide reliable evidence that the true concentration of the solution is actually not 5 mg/dl.