Experiment 41 Advance Study Assignment: Preparation of Aspirin 1. Calculate the theoretical yield of aspirin to be obtained in this experiment, starting with 2.0 g of salicylic acid and 5.0 mL of acetic anhydride (density

The theoretical yield of aspirin is 2.61g

Explanation:

The balanced equation is

Salicylic acid + Acetic anhydride ---> Acetylsalicylic acid + Acetic acid  

Number of moles salicylic acid = (2.0g) / (138 g/mol) = 0.0145 mol  

Mass of acetic anhydride = (1.08g/ml ) * (5.0 mL)  = 5.4g

Number of moles of acetic anhydride = 5.4g / (102g/mol) = 0.0529 mol

 As we can see in the reaction equation

1 mol of acetic anhydride  produce 1 mol aspirin

OR

0.0145 mol salicylic acid produces 0.0145 mol aspirin.

Mass of aspirin produced = 0.0145 mol * (180.157g/mol)

The theoretical yield of aspirin is 2.61g

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