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Chemistry, 27.11.2020 04:40 haileyparrill703

Intermediate filaments are uniquely non-polar and built by lateral bundling in five steps: 1. synthesis of an alpha-helical monomer
2. formation of a coiled-coil dimer
3. formation of a staggered tetramer of two coiled-coil dimers
4. lateral association of 8 tetramers
5. addition of 8 tetramers to a growing filament.

At what step is polarity lost?

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