Which characteristics of weak noncovalent interactions enable the assembly, stability, and functions of biomolecules? (pick one or more) A. They are readily reversible, whereas covalent bonds require a much larger input of energy to break.

B. They have a large cumulative effect, although individual interactions are relatively weak.

C. They are stable, requiring a large amount of energy to break.

D. They are not affected by the surrounding aqueous environment.