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Chemistry, 26.03.2020 02:44 gennhill14
Secondary amines add to aldehydes and ketones to give enamines. Enamines are formed in a reversible, acid-catalyzed process that begins with nucleophilic addition of the secondary amine to the carbonyl group, followed by transfer of the proton to yield a neutral carbinolamine. Protonation of the hydroxyl group converts it into a good leaving group, however there is no hydrogen left on the nitrogen to be lost to form a neutral imine product. Instead, a proton is lost from the neighboring carbon to form an enamine. Draw curved arrows to show the movement of electrons in this step of the mechanism.
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Secondary amines add to aldehydes and ketones to give enamines. Enamines are formed in a reversible,...
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