Go'=30.5 kJ/mol
a) Calculate the equilibrium constant for this reaction at 25C.
b) Because deltaGo' assumes standard pH of 7, the equilibrium constant calculated in (a) corresponds to Keq'= [oxaloacetate] [NADH]/ [L-malate] [NAD+]
The measured concentration of L-malate in rat liver mitochondria is about 0.20 mM when [NAD+]/[NADH] is 10. Calculate the concentration of oxaloaceteate at pH 7 in mitochondria.
c) To appreciate the magnitude of the mitochondrial oxaloacetate concentration, calculate the number of oxaloacetate molecules in a single rat mitochodrion. Assume the mitochondrion is a sphere of diameter 2.0 micro meters.
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Go'=30.5 kJ/mol
a) Calculate the equilibrium constant for this reaction at 25C.
b)...
a) Calculate the equilibrium constant for this reaction at 25C.
b)...
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