Chemistry, 23.12.2019 20:31 Victor3756

The primary amino acid sequence of the epidermal growth factor receptor (egfr) contains an invariant lysine amino acid essential for kinase activity. substitution of this essential lysine by any other amino acid blocks the capacity of the receptor to phosphorylate targets. what stage of receptor activation is disrupted by substitution of the invariant lysine with another amino acid?

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The primary amino acid sequence of the epidermal growth factor receptor (egfr) contains an invariant...